catalyst calendar
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ZYME biotech catalysts & pipeline

ZYMEWORKS INC · Data as of 2026-10-25

Upcoming catalysts

ZW209 — IND submission

in 2026

We anticipate submitting an IND to commence Phase 1 clinical studies for ZW209 in 2026, with equivalent non-U.S. applications to be submitted thereafter.
Source filing

ZW1528 — IND submission

in 2027

We anticipate submitting a regulatory filing to commence Phase 1 clinical studies for ZW1528 in 2027.
Source filing

EmpowHER-303 — Topline data

Sep 2027–Apr 2028

The EmpowHER-303 trial is expected to complete patient enrollment in mid-2027 with top-line data expected by the end of 2027 or early 2028.
Source filing

pasritamig — Conference presentation

H2 2026

Johnson and Johnson Innovative Medicine (J&J) expect to present Phase 1b clinical data for pasritamig, a first-in-class bispecific antibody against KLK2, in combination with JNJ-9401 in patients with advanced prostate cancer who have progressed after multiple lines of therapy, during the second half of 2026.
Source filing

zanidatamab — Topline data

Q3 2026

The top-line results from the second interim overall survival analysis for the HERIZON-GEA-01 trial doublet regimen are expected in the third quarter of 2026.
Source filing

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